Skip to main content

Advertisement

Table 1 Median, (25th and 75th percentiles) and percentage of median deviation between initial and follow-up samples of clinical scoring and the biomarkers recommended by IRIS. Group 1: dogs that showed proteinuria (UPC > 0.5) before treatment which did not decrease or even increased after treatment; Group 2: dogs that showed proteinuria (UPC > 0.5) before treatment which decreased after treatment

From: Evaluation of various biomarkers for kidney monitoring during canine leishmaniosis treatment

Parameter Group 1 (n = 6) Group 2 (n = 12) Reference values at authors laboratory
Inital Follow up % median deviation Inital Follow up % median deviation
Clinical Scoring 7 (6–8.2) 4 (2.5–4.2) −42 9 (3–15) 2 (0.5–7) −77  
UPC 1.492 (0.669–5.401) 2.270 (0.817–6.815) 52.14 1.318 (0.830–3.087) 0.432 (0.215–1.038)*** −67.22 <0.2
sCr (mg/dL) 0.88 (0.55–1.04) 0.92 (0.55–1.06) 1.04 0.69 (0.51–0.92) 0.94 (0.66–1.09) 13.62 <1.4
sSDMA (μg/dL) 10.40 (6.67–20.51) 9.91 (7.47–12.33) −9.52 10.95 (7.85–16.35) 11.15 (8.57–12.18) 1.01 <14
  1. ***P < 0.001 compared to baseline