TY - JOUR AU - Buntenkötter, Kathrin AU - Osmers, Maren AU - Schenk, Ina AU - Schänzer, Wilhelm AU - Machnik, Marc AU - Düe, Michael AU - Kietzmann, Manfred PY - 2017 DA - 2017/01/19 TI - Pharmacokinetics and in vitro efficacy of salicylic acid after oral administration of acetylsalicylic acid in horses JO - BMC Veterinary Research SP - 28 VL - 13 IS - 1 AB - Although acetylsalicylic acid (ASA) is not frequently used as a therapeutic agent in horses, its metabolite SA is of special interest in equestrianism since it is a natural component of many plants used as horse feed. This led to the establishment of thresholds by horse sport organizations for SA in urine and plasma. The aim of this study was to investigate plasma and urine concentrations of salicylic acid (SA) after oral administration of three different single dosages (12.5 mg/kg, 25 mg/kg and 50 mg/kg) of acetylsalicylic acid (ASA) to eight horses in a cross-over designed study. SN - 1746-6148 UR - https://doi.org/10.1186/s12917-017-0955-1 DO - 10.1186/s12917-017-0955-1 ID - Buntenkötter2017 ER -