Fig. 4

Immunohistochemistry study of HSP70 expression in the stomach mucosa of SD male rats. G1 (Normal control group), G2 (Ulcer control group), G3 (Omeprazole), G4 (62.5 mg/kg), G5 (125 mg/kg), G6 (250 mg/kg) and G7 (500 mg/kg). HSP70 protein expression was up-regulated in animals pre-treated with C. barometz in a dose-dependent manner and HSP70 protein expression was also up-regulated with omeprazole. Down-regulation appeared in the ulcerated control group (Scale bar = 100 μm). All data are stated as the mean ± SEM. The mean difference was significant at the P < 0.05 level compared to the normal control group