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Table 8 Kinetic data (mean ± SD) collected during walking in the control and ER-Bup groups

From: Pilot evaluation of a novel unilateral onychectomy model and efficacy of an extended release buprenorphine product

 

Treatment groups

Treatment effect

 

Variable

Control

ER-Bup

P-values

Group difference in time

SI for PVF

(−54.61 ± 27.98)

(−41.57 ± 22.03)

0.0002*

ER-Bup > control at 6, 54 h

SI for VI

(−36.33 ± 25.59)

(−26.13 ± 21.89)

<.0001*

ER-Bup > control at 6, 54 h

  1. *indicates significant difference between groups (<0.05)
  2. PVF Peak vertical force, VI vertical impulse, SI symmetry indices, ER-Bup extended release formulation of buprenorphine HCL