Skip to main content

Table 6 Landing data (summary variables for postoperative time points compared to baseline) for each treatment group and tabluation of treatment effects

From: Pilot evaluation of a novel unilateral onychectomy model and efficacy of an extended release buprenorphine product

   Treatment groups Treatment effect  
Variable Control ER-Bup P-values Group differences at individual time points
PVF OP (−63.97 ± 45.59) (−50.50 ± 37.44) 0.0026* ER-Bup > control at 6, 54 h
NO 23.69 ± 40.23 11.63 ± 37.58 0.0169*  
VI OP (−3.89 ± 3.50) (−6.25 ± 3.22) <0.0001* ER-Bup < control at 6, 30, 48, 72 h
NO 8.99 ± 7.23 1.87 ± 4.50 <0.0001* ER-Bup < control at all time points
SI PVF (−52.03 ± 26.02) (−38.72 ± 18.63) <0.0001* ER-Bup > control at 6, 24, 54 h
VI (−72.28 ± 29.47) (−54.96 ± 27.10) <0.0001* ER-Bup > control at 6, 30, 54 h
Tf1f2 0.012 ± 0.021 0.008 ± 0.010 0.076  
Tf1h1 0.014 ± 0.029 (−0.015 ± 0.023) <0.0001* ER-Bup < control at all time points
  1. Mean ± SD, *indicates significant difference between groups (<0.05)
  2. OP Operated limb, NO Non-operated limb, PVF Peak vertical force, VI vertical impulse, SI symmetry indices, Tf1f2 Time between first and second forelimb strike, Tf1h1 Time between first forelimb and first hindlimb strike, ER-Bup extended release formulation of buprenorphine HCL