|  | Treatment groups | Treatment effect |  | |
---|---|---|---|---|---|
Variable | Control | ER-Bup | P-values | Group differences at individual time points | |
PVF | OP | (−63.97 ± 45.59) | (−50.50 ± 37.44) | 0.0026* | ER-Bup > control at 6, 54 h |
NO | 23.69 ± 40.23 | 11.63 ± 37.58 | 0.0169* |  | |
VI | OP | (−3.89 ± 3.50) | (−6.25 ± 3.22) | <0.0001* | ER-Bup < control at 6, 30, 48, 72 h |
NO | 8.99 ± 7.23 | 1.87 ± 4.50 | <0.0001* | ER-Bup < control at all time points | |
SI | PVF | (−52.03 ± 26.02) | (−38.72 ± 18.63) | <0.0001* | ER-Bup > control at 6, 24, 54 h |
VI | (−72.28 ± 29.47) | (−54.96 ± 27.10) | <0.0001* | ER-Bup > control at 6, 30, 54 h | |
Tf1f2 | 0.012 ± 0.021 | 0.008 ± 0.010 | 0.076 |  | |
Tf1h1 | 0.014 ± 0.029 | (−0.015 ± 0.023) | <0.0001* | ER-Bup < control at all time points |