Fig. 5

Effect of treatment with ER-Bup on landing kinetic data. a Peak vertical force (PVF) for operated limb (OP); b Vertical impulse (VI) for OP; c Symmetry indices (SI) for PVF; d SI for VI. Assessments were made 24 and 48 h initial and second surgery (baseline) and 6, 24, 30, 48, 54, and 72 h after surgery. The average baseline value was subtracted from the measured value at each time point in the analysis. Line graphs showing the changes from baseline in each gait parameter over study period. The mean difference ± SD in control group and extended release formulation of buprenorphine HCL (ER-Bup) group at various time points after onychectomy (n = 4). Orange solid line is control group, blue dotted line is ER-Bup group. Negative value of SI means the cat put less weight on operated limb after surgery.* indicates significant difference between groups (<0.05)