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Fig. 3 | BMC Veterinary Research

Fig. 3

From: Pilot evaluation of a novel unilateral onychectomy model and efficacy of an extended release buprenorphine product

Fig. 3

Probability of pain score having a value equal to baseline versus time. The blue line represents the ER-Bup treatment and the red line represents control treatment. The left panel represents the sequence of saline, then ER-Bup injection, while right panel ER-Bup, then saline injection. Horizontal reference line at Probability = 0.5. The predicted time at which a probability of 0.5 is reached, similar to an LD50, is around the first time measurement (3 h) in the ER-Bup group (blue curves) in the left and right graphs. For the control group (red curves) the time for probability of 0.5 is quite different for the two periods, around 18 for the right graph and 55 for the left graph

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