Skip to main content
Fig. 2 | BMC Veterinary Research

Fig. 2

From: Pseudorabies virus infection (Aujeszky’s disease) in an Iberian lynx (Lynx pardinus) in Spain: a case report

Fig. 2

Histopathology and immunohistochemistry. Iberian lynx a Cerebrum. The leptomeninges and subarachnoid space were infiltrated by mononuclear cells (arrows) HE (bar = 25 μm). b Cerebrum. Mononuclear cellular infiltrates around blood vessels and neuropil. Demyelination and spongiosis. HE. (bar = 35 μm). c Cerebrum. Glial satellitosis (arrows). HE. (bar = 40 μm). d Cerebrum. Neuronal necrosis and neuronophagia (black arrows). Satellitosis (white arrows). HE. (bar = 35 μm). e Cerebrum. Neuronal intranuclear inclusion bodies (arrow). HE. (bar = 50 μm). f Tonsils. Positive immunostaining for PRV antigen in lymphocytes (white arrow), plasma cells (red arrow) and macrophages (black arrow). PDM. DAB chromogen. (bar = 40 μm). g Stomach. PRV antigen was detected in gastric glandular epithelial cells. PDM. DAB chromogen. (bar = 35 μm). h Cerebrum. Immunohistochemical PRV detection in neurons (arrows). PDM. DAB chromogen. (bar = 40 μm). i Cerebellum. Immunohistochemical demonstration of PRV presence in glial cells of white matter of the cerebellum. Some cells are necrotic (arrow). PDM. DAB chromogen. (bar = 40 μm)

Back to article page