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Table 3 MMP-2, MMP-9, TIMP-1 and TIMP-2 ELISA and MMP-8 fluorimetry measurements, the results are expressed as mean ± SD

From: Metalloproteinases and their inhibitors are influenced by inhalative glucocorticoid therapy in combination with environmental dust reduction in equine recurrent airway obstruction

 

n

Before therapy

After therapy

P-value

MMP-2 ELISA [pg/ml]

10

4.93 ± 0.91

3.54 ± 0.71

0.005

MMP-9 ELISA [ng/ml]

10

414.59 ± 119.6

282.29 ± 101.19

0.005

TIMP-1 ELISA [pg/ml]

10

308.80 ± 7.44

249.78 ± 59.56

0.005

TIMP-2 ELISA [ng/ml]

10

26.20 ± 1.49

18.76 ± 2.79

0.002

MMP-8 Fluorimetry [RFU]

10

0.57 ± 0.85

0.1 ± 0.11

0.005

MMP-2 zymography

10

12570.98 ± 9164.32

5827.45 ± 5250.42

0.028

MMP-9 zymography

10

11176.68 ± 11255.3

2942.95 ± 2440.24

0.022