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Table 2 Antibodies, clinical signs and lung lesions in animals

From: An inactivated gE-deleted pseudorabies vaccine provides complete clinical protection and reduces virus shedding against challenge by a Chinese pseudorabies variant

Groups

A

B

C

D

E

F

ELISA antibodies against PRV gB or gE

B.V.

gB+

0a/5b

0/5

0/5

0/5

0/5

0/5

gE+

0/5

0/5

0/5

0/5

0/5

0/5

7d P.V.

gB+

2/5

5/5

2/5

5/5

0/5

0/5

gE+

0/5

0/5

0/5

0/5

0/5

0/5

14d P.V.

gB+

5/5

5/5

5/5

5/5

0/5

0/5

gE+

0/5

0/5

0/5

0/5

0/5

0/5

21d P.V.

gB+

5/5

5/5

5/5

5/5

0/5

0/5

gE+

0/5

0/5

0/5

0/5

0/5

0/5

14d P.C.

gB+

5/5

5/5

5/5

5/5

2/2

0/5

gE+

5/5

5/5

5/5

5/5

2/2

0/5

Mean titers of neutralizing antibodies

AH02LA

B.V.

<2c

<2

<2

<2

<2

<2

7d P.V.

<2

<2

<2

<2

<2

<2

14d P.V.

<2

0.4

<2

<2

<2

<2

21d P.V.

2.00

2.80

<2

1.20

<2

<2

28d P.V.

2.60

3.40

2.40

2.60

<2

<2

35d P.V.

4.60

5.20

3.60

3.20

<2

<2

42d P.V.

4.60

5.60

3.80

3.20

<2

<2

49d P.V.

5.20

6.20

4.20

3.00

<2

<2

Bartha K61

B.V.

<2

<2

<2

<2

<2

<2

7d P.V.

<2

<2

<2

<2

<2

<2

14d P.V.

<2

0.4

<2

<2

<2

<2

21d P.V.

1.20

2.24

1.2

1.60

<2

<2

28d P.V.

2.40

3.08

2.60

3.20

<2

<2

35d P.V.

4.60

4.80

4.60

3.20

<2

<2

42d P.V.

4.80

5.20

4.80

3.60

<2

<2

49d P.V.

5.40

5.60

5.20

3.40

<2

<2

Clinical signs and lung lesions post challenge

Morbidity

1/5

0/5

4/5

3/5

5/5

0/5

Duration of clinical signs(days)

1

-

2–4

2–3

4–7

-

Mortality

0/5

0/5

0/5

0/5

4/5

0/5

Lung lesions

0/5

0/5

2/5

1/5

5/5

0/5

  1. B.V means before vaccination, P.V means post vaccination, P.C means post challenge. “a” indicates the number of piglets positive;“b” indicates the number of piglets in the group. “c” indicates mean titers of neutralizing antibody of each group expressed as nlog2 of highest dilution at which no CPE was observed
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BMC Veterinary Research

ISSN: 1746-6148

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