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Table 7 Log-rank test results for dogs with idiopathic and structural epilepsy

From: Retrospective epidemiological study of canine epilepsy in Japan using the International Veterinary Epilepsy Task Force classification 2015 (2003–2013): etiological distribution, risk factors, survival time, and lifespan

Variables

All epilepsy cases (years)

IdE (years)

StE (years)

n (dead)

median (95 % CI)

P value

n (dead)

median (95 % CI)

P value

n (dead)

median (95 % CI)

P value

Gender

 Male

52 (30)

8.9 (5.6–11.8)

0.26

37 (18)

11.3 (7.3–12.6)

0.45

15 (12)

4.5 (0.4–10.4)

0.20

 Female

42 (13)

10.1 (9.2–∞)

27 (7)

10.1 (9.2–∞)

15 (6)

NA (1.9–∞)

Status of neuter

 Intact

53 (26)

10.2 (8.1–11.8)

0.31

35 (15)

10.4 (8.9–14.5)

0.31

18 (11)

10.2 (1.3–∞)

0.46

 Neuter

41 (17)

9.3 (6.3–∞)

29 (10)

9.3 (6.3–∞)

12 (7)

6.7 (0.4–∞)

Body weight

 < 6.6 kg

47 (20)

10.2 (6.7–14.5)

0.26

31 (11)

11.9 (7.5–∞)

0.28

16 (9)

6.7 (3.3–∞)

0.27

 ≥ 6.6 kg

47 (23)

9.3 (7.1–10.4)

33 (14)

10.1 (7.3–∞)

14 (9)

4.0 (0.4–∞)

Seizure frequency at last follow-up

 < 0.3 sz/month

48 (16)

11.8 (10.4–14.5)

<0.01

37 (11)

11.9 (11.3–14.5)

<0.01

11 (5)

10.4 (0.58–∞)

0.06

 ≥ 0.3 sz/month

46 (27)

7.3 (4.5–9.2)

27 (14)

8.9 (5.3–10.1)

19 (13)

4.5 (1.2–∞)

Epileptic seizure type

 FES

20 (6)

8.9 (3.3–∞)

0.77

15 (4)

8.9 (2.9–∞)

0.20

5 (2)

NA (0.2–∞)

0.89

 GES

51 (26)

10.4 (7.3–11.9)

30 (12)

11.3 (10.1–14.5)

21 (14)

5.6 (1.2–10.4)

 FEvG

23 (11)

8.1 (6.3–∞)

19 (9)

9.2 (5.3–∞)

4 (2)

6.7 (6.7–∞)

Development of CS

 Yes

43 (22)

9.2 (4.1–11.3)

0.06

26 (11)

10.4 (4.1–∞)

0.21

17 (11)

4.5 (1.1–∞)

0.18

 No

51 (21)

10.1 (8.1–11.9)

38 (14)

10.1 (8.1–14.5)

13 (7)

6.7 (3.3–∞)

Development of SE

 Yes

16 (9)

10.1 (4.1–11.9)

0.93

13 (7)

10.1 (4.1–∞)

0.42

3 (2)

10.4 (3.3–∞)

0.54

 No

78 (34)

10.2 (7.5–11.8)

51 (18)

10.4 (8.9–∞)

27 (16)

6.7 (1.3–∞)

Using AEDs at last follow-up

 None or monotherapy

58 (26)

10.4 (7.1–12.6)

0.48

37 (14)

11.9 (7.5–14.5)

0.29

22 (12)

5.6 (1.3–∞)

0.50

 Polytherapy

36 (17)

9.3 (6.7–10.4)

27 (11)

9.3 (7.3–11.3)

8 (6)

6.7 (1.1–∞)

  1. IdE idiopathic epilepsy, StE structural epilepsy, 95 % CI 95 % confidence interval, GES generalized epileptic seizure, FES focal epileptic seizure, sz seizure, FEvG focal epileptic seizure evolving into generalized epileptic seizures, CS cluster seizures, SE epilepticus status, AED antiepileptic drug, NA not available