Pro-inflammatory cytokines and structural biomarkers are effective to categorize osteoarthritis phenotype and progression in Standardbred racehorses over five years of racing career

Table 8 Correlation between different cytokines and structural biomarkers in the PTOA affected race horses

		IL-1ß					IL-6					TNF-α					COMP					CTX-II
		T0	T1	T2	T3	T4	T0	T1	T2	T3	T4	T0	T1	T2	T3	T4	T0	T1	T2	T3	T4	T0	T1	T2	T3	T4
IL-1ß	S	1.0	1.0	1.0	1.0	1.0	0.40	–	–	–	–	–	–	–	–	–	–	–	–	–	–	–	–	–	0.41	–
IL-1ß	SF	1.0	1.0	1.0	1.0	1.0	0.69	–	–	–	–	–	–	–	0.68	0.58	0.66	0.50	–	0.48	0.45	–	–	–	–	–
IL-6	S						1.0	1.0	1.0	1.0	1.0	–	–	–	0.43	–	0.53	–	0.41	–	0.52	–	0.42	–	–	–
IL-6	SF						1.0	1.0	1.0	1.0	1.0	–	–	–	–	–	0.61	–	–	–	–	–	–	0.58	–	–
TNF-α	S											1.0	1.0	1.0	1.0	1.0	–	–	–	–	–	–	–	–	–	–
TNF-α	SF											1.0	1.0	1.0	1.0	1.0	–	–	–	–	–	0.51	–	–	0.69	0.71
COMP	S																1.0	1.0	1.0	1.0	1.0	–	–	–	–	–
COMP	SF																1.0	1.0	1.0	1.0	1.0	–	–	–	–	–
CTXII	S																					1.0	1.0	1.0	1.0	1.0
CTXII	SF																					1.0	1.0	1.0	1.0	1.0

Only the coefficients of (r) of significant groups are shown in bold, for clarity

ISSN: 1746-6148