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Table 8 Correlation between different cytokines and structural biomarkers in the PTOA affected race horses

From: Pro-inflammatory cytokines and structural biomarkers are effective to categorize osteoarthritis phenotype and progression in Standardbred racehorses over five years of racing career

   IL-1ß IL-6 TNF-α COMP CTX-II
   T0 T1 T2 T3 T4 T0 T1 T2 T3 T4 T0 T1 T2 T3 T4 T0 T1 T2 T3 T4 T0 T1 T2 T3 T4
IL-1ß S 1.0 1.0 1.0 1.0 1.0 0.40 – – – – – – – – – – – – – – – – – 0.41 –
SF 1.0 1.0 1.0 1.0 1.0 0.69 – – – – – – – 0.68 0.58 0.66 0.50 – 0.48 0.45 – – – – –
IL-6 S       1.0 1.0 1.0 1.0 1.0 – – – 0.43 – 0.53 – 0.41 – 0.52 – 0.42 – – –
SF       1.0 1.0 1.0 1.0 1.0 – – – – – 0.61 – – – – – – 0.58 – –
TNF-α S            1.0 1.0 1.0 1.0 1.0 – – – – – – – – – –
SF            1.0 1.0 1.0 1.0 1.0 – – – – – 0.51 – – 0.69 0.71
COMP S                 1.0 1.0 1.0 1.0 1.0 – – – – –
SF                 1.0 1.0 1.0 1.0 1.0 – – – – –
CTXII S                      1.0 1.0 1.0 1.0 1.0
SF                      1.0 1.0 1.0 1.0 1.0
  1. Only the coefficients of (r) of significant groups are shown in bold, for clarity
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