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Table 7 Correlation between biomarkers percentual change (Δ) and percentual change of radiological score (Δ) in the subsequent year, in PTOA affected horses only

From: Pro-inflammatory cytokines and structural biomarkers are effective to categorize osteoarthritis phenotype and progression in Standardbred racehorses over five years of racing career

  Δ mean radiographical score of T (x+1)−T (x)
T (x) = T1 T (x) = T2 T (x) = T3
ΔIL-1b of T (x)−T (x−1) Serum
Synovial Fluid
ΔIL-6 of T (x)−T (x−1) Serum r  = 0.42 (p  = 0.041)
Synovial Fluid
ΔTNF-a of T (x)−T (x−1) Serum
Synovial Fluid r  = 0.38 (p  = 0.058) r  = 0.435 (p  = 0.030)
ΔCOMP of T (x)−T (x−1) Serum r  = 0.39 (p  = 0.053)
Synovial Fluid
ΔCTXII of T (x)−T (x−1) Serum
Synovial Fluid
  1. Significant correlations are represented in bold