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Table 7 Correlation between biomarkers percentual change (Δ) and percentual change of radiological score (Δ) in the subsequent year, in PTOA affected horses only

From: Pro-inflammatory cytokines and structural biomarkers are effective to categorize osteoarthritis phenotype and progression in Standardbred racehorses over five years of racing career

 

Δ mean radiographical score of T (x+1)−T (x)

T (x) = T1

T (x) = T2

T (x) = T3

ΔIL-1b of T (x)−T (x−1)

Serum

–

–

–

Synovial Fluid

–

–

–

ΔIL-6 of T (x)−T (x−1)

Serum

–

–

r  = 0.42 (p  = 0.041)

Synovial Fluid

–

–

–

ΔTNF-a of T (x)−T (x−1)

Serum

–

–

–

Synovial Fluid

–

r  = 0.38 (p  = 0.058)

r  = 0.435 (p  = 0.030)

ΔCOMP of T (x)−T (x−1)

Serum

r  = 0.39 (p  = 0.053)

–

–

Synovial Fluid

–

–

–

ΔCTXII of T (x)−T (x−1)

Serum

–

–

–

Synovial Fluid

–

–

–

  1. Significant correlations are represented in bold