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Table 6 Synovial Fluid and Serum correlations at different time-points

From: Pro-inflammatory cytokines and structural biomarkers are effective to categorize osteoarthritis phenotype and progression in Standardbred racehorses over five years of racing career

Synovial fluid/Serum concentration

T0

T1

T2

T3

T4

PTOA group

IL-1b

–

–

–

–

r = 0.43*

IL-6

r = 0.43*

–

–

–

r = 0.51**

TNF-a

–

–

–

r = 0.53**

–

COMP

–

–

–

–

–

CTXII

–

–

–

r = 0.57**

r = 0.63***

C group

IL-1b

–

–

–

–

–

IL-6

–

–

r = −0.85*

–

–

TNF-a

–

–

–

r = 0.87*

–

COMP

–

–

–

–

–

CTXII

–

–

–

–

–

  1. Correlations of pro-inflammatory cytokines and structuralbiomarkers values, in the synovial fluid and serum, at different time-points, in both the PTOA and C groups, over the 5 years of the study. P-values and coefficient of regression (r) are shown. Significant correlations are represented as bolded R-values with the superscript star. Key: *:p < 0.05;**:p < 0.01;***:p < 0.001