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Fig. 4 | BMC Veterinary Research

Fig. 4

From: Pro-inflammatory cytokines and structural biomarkers are effective to categorize osteoarthritis phenotype and progression in Standardbred racehorses over five years of racing career

Fig. 4

Temporal course of OA biomarkers levels and corresponding clinical scores in the PTOA group. Percentual variations of OA biomarker levels and corresponding radiographic and lameness scores, in the PTOA group of racehorses (n = 25), during 5 years of racing activity. Panel a refers to values in the sera. Panel b refers to the synovial fluid values. Data for each time point represent the mean levels of IL-1ß, IL-6, TNF-α, CTXII, COMP, Radiographic score and Lameness score. Standard deviation (SD) error bars are not plotted in these graphs for clarity. Reference value at T0 is delineated (dotted line). *p < 0.05 versus level at previous time-point. **p < 0.001 versus level at previous time-point

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