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Table 1 Characterisation of dogs with osteoarthritis (OA), suppurative arthritis and healthy dogs

From: Measurement of serum C-reactive protein concentration for discriminating between suppurative arthritis and osteoarthritis in dogs

Parameter Median (IQR) P values
Osteoarthritis (n = 34) Suppurative arthritis (n = 31) Healthy (n = 17) Suppurative arthritis vs OA Healthy vs OA
Age (years) 2.7 (0.9-6.2) 4.2 (1.6-7.5) 1.8 (1.2-2.7) 0.19 0.33
Weight (kg) 32 (24–39) 28 (19–33) 14 (13–15) 0.11 <0.001
Serum CRP (mg/l) 0.73 (<0.50-2.45) 107 (43–145) 1.26 (0.62-2.32) <0.001 0.29
Serum IL-6a (pg/ml) 15.0 (10.2-26.5) 101 (47.7-243) 9.2 (8.0-11.4) <0.001 0.07
Synovial fluid IL-6b (pg/ml) 131 (21.5-450) 19 800 (4030- > 20 000) <2.4 (<2.4-3.9) <0.001 <0.001
Sex (male/female) 17/17 18/13 12/5 0.62 0.23
NSAID treatment (treatment/no treatment) 22/12 5/26 0/17 <0.001 <0.001
  1. Serum C-reactive protein (CRP), serum interleukin (IL) 6 and synovial fluid IL-6 concentrations in dogs with osteoarthritis (OA), suppurative arthritis, and in healthy dogs. Data is presented as median and interquartile range (IQR). Pairwise comparisons were performed between groups of dogs with OA and suppurative arthritis, and between dogs with OA and healthy dogs. NSAID; non-steroidal anti-inflammatory drug
  2. aSerum IL-6 results available from dogs with OA (n = 29), suppurative arthritis (n = 29), and healthy dogs (n = 7)
  3. bSynovial fluid IL-6 results available from dogs with OA (n = 19), suppurative arthritis (n = 29), and from healthy dogs (n = 14)