Fig. 1
From: Identification and characterization of two CD4 alleles in Microminipigs
Comparison of amino-acid sequences of porcine CD4 alleles. Deduced amino-acid sequences of CD4.A and CD4.B were compared with those of the swine CD4 reference sequence [GenBank: NP_001001908]. Amino-acid sequences of two CD4 alleles reported in NIH miniature swine [GenBank: CAA46583 (CD4.1), CAA46584 (CD4.2)] also were compared with CD4.A and CD4.B. (-) indicates gaps or absence of sequence corresponding to [GenBank: NP_001001908]. (.) indicates having identical sequence with that of [GenBank: NP_001001908]. Arrow indicates the putative boundary of each exon. Regions of leader sequence, four extracellular Ig-like domains (Domain 1-4), joining region (JR 1-4), transmembrane (TM) domain, and cytoplasmic domain are also shown. <−−− > indicates CDR1-3 like region in domain 1. An outlined circle indicates that the amino-acid side chain has changed the polarity in association with amino-acid substitution. An outlined square indicates that the amino-acid side chain has changed the charge in association with amino-acid substitution