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Table 3 Pigs vaccinated with E2 subunit vaccine developed high titers of anti-CSFV neutralizing antibodies

From: Pigs immunized with a novel E2 subunit vaccine are protected from subgenotype heterologous classical swine fever virus challenge

Treatment

Pig #

35 DPV

15 DPC

Treatment

Pig #

35 DPV

15 DPC

(−/−)

51

0

0

(−/+)

56

0

>160

(−/−)

52

0

0

(−/+)

57

0

0

(−/−)

53

0

0

(−/+)

58

0

0

(−/−)

54

0

0

(−/+)

59

0

0

(−/−)

55

0

0

(−/+)

60

0

0

One-dose

61

15

10,240

Two-dose

66

960

7680

One-dose

62

240

>10,240

Two-dose

67

640

7680

One-dose

63

320

>10,240

Two-dose

68

1920

10,240

One-dose

64

20

>10,240

Two-dose

69

7680

7680

One-dose

65

640

5120

Two-dose

70

480

2560

  1. DPV day post vaccination (first dose), DPC day post challenge. Pigs were challenged on 35 DPV
  2. (−/−): Control pigs without challenge; (−/+): Control pigs challenged with CSFV
  3. One-dose: Pigs vaccinated with one dose KNB-E2 and then challenged with CSFV
  4. Two-dose: Pigs vaccinated with KNB-E2 twice and then challenged with CSFV