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Table 3 Comparison of blood parameters between dogs co-infected with B. canis and D. repens and infected only with B. canis in different severity classes

From: The prevalence of Dirofilaria repens in cats, healthy dogs and dogs with concurrent babesiosis in an expansion zone in central Europe

General symptom level

Parameter

Mean (± SEM) in dogs infected with B.canis + D.repens

Mean (± SEM) in dogs infected only with B. canis

F and P

I. Anemia

 Level 0:

Erythrocytes (T/l)

6.07 ± 0.181

6.00 ± 0.610

F 2, 40 = 0.708; P = 0.408

Leucocytes (G/l)

5.12 ± 0.756

4.20 ± 2.661

F 2, 40 = 2.734; P = 0.082

Thrombocytes (G/l)

52.56 ± 6.871

23.00 ± 24.188

F 2, 40 = 6.866; P = 0.004

Hematocrit (l/l)

0.377 ± 0.014

0.450 ± 0.046

F 2, 40 = 0.044; P = 0.835

 Level 1:

Erythrocytes (T/l)

4.80 ± 0.294

5.08 ± 0.431

 

Leucocytes (G/l)

4.39 ± 0.810

5.15 ± 1.881

 

Thrombocytes(G/l)

38.06 ± 7.360

92.50 ± 17.103

 

Hematocrit(l/l)

0.311 ± 0.022

0.365 ± 0.033

 

 Level 2:

Erythrocytes (T/l)

3.64 ± 0.249

3.95 ± 0.431

 

Leucocytes (G/l)

7.83 ± 1.402

11.50 ± 1.881

 

Thrombocytes (G/l)

39.89 ± 12.748

125.50 ± 17.103

 

Hematocrit (l/l)

0.247 ± 0.019

0.265 ± 0.033

 

II. Hepatic dysfunction

 Level 0:

AST (U/l)

34.60 ± 24.153

nd

F 1, 36 = 0.709; P = 0.407

ALT (U/l)

40.40 ± 51.35

nd

F 1, 36 = 0.044; P = 0.835

ALP (U/l)

102.00 ± 48.093

nd

F 1, 36 = 0.360; P = 0.554

 Level 1:

AST (U/l)

93.78 ± 15.868

81.00 ± 38.189

 

ALT (U/l)

60.33 ± 33.736

82.00 ± 81.192

 

ALP (U/l)

151.28 ± 31.726

119.50 ± 76.041

 

 Level 2:

AST (U/l)

307.67 ± 23.815

361.67 ± 31.181

 

ALT (U/l)

378.08 ± 50.632

466.00 ± 66.293

 

ALP (U/l)

259.00 ± 47.420

641.67 ± 62.087

 

III. Renal dysfunction

 Level 0:

Creatinine (mg/dl)

0.87 ± 0.117

0.70 ± 0.334

F 2, 36 = 11.68; P = 0.000

Serum urea (mg/dl)

28.94 ± 8.127

29.75 ± 23.131

F 2, 36 = 16.16; P = 0.000

 Level 1:

Creatinine (mg/dl)

1.03 ± 0.236

0.90 ± 0.545

 

Serum urea (mg/dl)

52.88 ± 16.356

62.00 ± 37.773

 

 Level 2:

Creatinine (mg/dl)

2.55 ± 0.272

5.90 ± 0.545

 

Serum urea (mg/dl)

248.50 ± 18.886

527.00 ± 37.773

 
  1. P values derived from ANOVAs
  2. D. repens presence x anemia level on erythrocytes count; D. repens presence x anemia level on leucocytes count; D. repens presence x anemia level on thrombocytes count
  3. D. repens presence x hepatic dysfunction level on AST activity; D. repens presence x hepatic dysfunction level on ALT activity; D. repens presence x hepatic dysfunction level on ALP activity; D. repens presence x renal dysfunction level on serum creatinine; D. repens presence x renal dysfunction level on serum urea
  4. Nd- not done, the lack of cases in this group