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Table 2 Comparison of the selected parameters for the estimation of the severity of the three general symptoms, then used for classification of the severity of the babesiosis (classes 1–3)

From: The prevalence of Dirofilaria repens in cats, healthy dogs and dogs with concurrent babesiosis in an expansion zone in central Europe

Summarized symptom and parameters ± SEM Severity class P
Class 0 (normal) Class 1 (mild) Class 2 (severe)
1. Anemia: n = 15 n = 14 n = 12  
 Erythrocytes (T/l) 5.98 ± 0.183 5.02 ± 0.187 3.20 ± 0.235 0.000
 Leukocytes (G/l) 4.89 ± 0.874 4.69 ± 0.896 9.06 ± 1.126 0.014
 Hematocrit (l/l) 0.402 ± 0.013 0.347 ± 0.013 0.213 ± 0.017 0.000
 Hemoglobin (mmol/l) 8.777 ± 0.286 7.558 ± 0.293 4.651 ± 0.368 0.000
 Thrombocytes (G/l) 45.17 ± 7.945 59.83 ± 8.143 68.43 ± 10.234 0.103 NS
2. Hepatic dysfunction: n = 5 n = 22 n = 10  
 AST (U/l) 32.13 ± 77.238 78.20 ± 43.727 315.33 ± 47.672 0.029
 ALT (U/l) 37.25 ± 96.948 66.58 ± 54.886 426.00 ± 59.838 0.011
 ALP (U/l) 112.50 ± 96.599 141.69 ± 54.840 451.19 ± 59.622 0.026
3. Renal dysfunction: n = 25 n = 7 n = 5  
 Creatinine (mg/dl) 0.802 ± 0.151 0.983 ± 0.240 4.23 ± 0.304 0.000
 Serum urea (mg/dl) 29.27 ± 10.459 55.92 ± 16.656 387.75 ± 21.116 0.000
  1. P-probability values from ANOVA tests
  2. Reference values for parameters and explanations as in legend to Table 1