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Table 2 Comparison of the selected parameters for the estimation of the severity of the three general symptoms, then used for classification of the severity of the babesiosis (classes 1–3)

From: The prevalence of Dirofilaria repens in cats, healthy dogs and dogs with concurrent babesiosis in an expansion zone in central Europe

Summarized symptom and parameters ± SEM

Severity class

P

Class 0 (normal)

Class 1 (mild)

Class 2 (severe)

1. Anemia:

n = 15

n = 14

n = 12

 

 Erythrocytes (T/l)

5.98 ± 0.183

5.02 ± 0.187

3.20 ± 0.235

0.000

 Leukocytes (G/l)

4.89 ± 0.874

4.69 ± 0.896

9.06 ± 1.126

0.014

 Hematocrit (l/l)

0.402 ± 0.013

0.347 ± 0.013

0.213 ± 0.017

0.000

 Hemoglobin (mmol/l)

8.777 ± 0.286

7.558 ± 0.293

4.651 ± 0.368

0.000

 Thrombocytes (G/l)

45.17 ± 7.945

59.83 ± 8.143

68.43 ± 10.234

0.103 NS

2. Hepatic dysfunction:

n = 5

n = 22

n = 10

 

 AST (U/l)

32.13 ± 77.238

78.20 ± 43.727

315.33 ± 47.672

0.029

 ALT (U/l)

37.25 ± 96.948

66.58 ± 54.886

426.00 ± 59.838

0.011

 ALP (U/l)

112.50 ± 96.599

141.69 ± 54.840

451.19 ± 59.622

0.026

3. Renal dysfunction:

n = 25

n = 7

n = 5

 

 Creatinine (mg/dl)

0.802 ± 0.151

0.983 ± 0.240

4.23 ± 0.304

0.000

 Serum urea (mg/dl)

29.27 ± 10.459

55.92 ± 16.656

387.75 ± 21.116

0.000

  1. P-probability values from ANOVA tests
  2. Reference values for parameters and explanations as in legend to Table 1