Evidence of scrapie transmission to sheep via goat milk

BMC Veterinary Research

Table 3 Details of sheep fed milk from scrapie-affected goats

Donor	Milk volume fed [litre]	Recipient	PRNP codon 141	First ante-mortem detection of PrP^sc (percentage of the survival time) or last negative rectal biopsy	Survival time [days of age]
G1383	87	1286^a	LL	803 (62 %)	1285
G1383	87	1287^a	LF	585 (44 %)	1325
G1415	82	1319^a	LL	1065 (95 %)	1122
G1415	82	1320^a	LF	795 (51 %)	1552
G1427	76^b	1294^a	LL	1045 (84 %)	1243
G1427	76^b	1293	LL	583 (45 %)	1284
BIM	63	1329	LL	1034 (80 %)	1298
BIM	67	1302	LF	800 (55 %)	1466
G1143	57	1324^a	LF	1366 (94 %)	1460
G1143	57	1323^a	LF	983 (66 %)	1486
BII	38^b	1321^a	LF	794 (60 %)	1333
BII	38^b	1322	LF	1064 (71 %)	1493
G1465	8	1333^a	LL	1358	1433
G1465	9	1332^a	LF	1761	1872
G1472	8	1330	LL	1361	1519
G1472	8	1331	LF	1761	1872
Control	––––	1310	LF	1771	1882
Control	––––	1318	LF	1768	1880
Control	––––	1325	LF	1762	1867
Control	––––	1334	LF	1758	1864
Control	––––	1338	LL	1752	1858

^aFemale; all other sheep were castrated males; ^bIncluded colostrum. Lambs were fed goat milk between 16 and 32 h (mean 24 h) after being born

ISSN: 1746-6148