Lymphocytic, cytokine and transcriptomic profiles in peripheral blood of dogs with atopic dermatitis

BMC Veterinary Research

Table 2 Percentage of lymphocyte subsets in peripheral blood of dogs with atopic dermatitis and healthy dogs

Lymphocytes subpopulations	% of cells in different subpopulations of white blood cells
Lymphocytes subpopulations	AD dogs	Control dogs	P value
Lymphocytes	45.2 ± 3.3	42.7 ± 6.5	0.7147
CD3⁺	25.67^* ± 3.02	35.90 ± 2.65	0.0408
B cells	3.81^* ± 0.68	6.24 ± 0.82	0.0373
CD3⁺ CD4⁺	67.40 ± 2.01	70.70 ± 1.94	0,1866
CD3⁺CD8⁺	19.56 ^** ± 0.87	14.71 ± 1.11	0.0023
CD4⁺/CD8⁺	3.86^* ± 0.33	5.31 ± 0.41	0.0132
CD4⁺CD25⁺ Foxp3⁺	1.54^*** ± 0.18	0.48 ± 0.08	<0.0001

The results are expressed as mean percentage of positive cells ± SEM, ratio CD4⁺/CD8⁺ was calculated as the ratio of absolute number of cells within the T lymphocytes population, symbol ^*represents the level of significance: P ≤ 0.05, **P ≤ 0.01, ***P ≤ 0.001

ISSN: 1746-6148