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Table 1 MIC/MPC distribution for four compounds with clinical isolates of R. anatipestifer (n = 105)

From: In vitro susceptibility of four antimicrobials against Riemerella anatipestifer isolates: a comparison of minimum inhibitory concentrations and mutant prevention concentrations for ceftiofur, cefquinome, florfenicol, and tilmicosin

Drug

Distribution of MIC and MPC values (μg/mL)

Concentrations

≤0.008

0.016

0.031

0.063

0.125

0.25

0.5

1

2

4

8

16

32

64

≥128

MIC50/MIC90

MIC distribution

                

 Ceftiofur

3

8

25

22

16

13

10

3

1

2

2

    

0.063/0.5

 Cefquinome

28

22

15

6

12

9

5

3

3

 

1

1

   

0.031/0.5

 Florfenicol

    

1

1

28

25

37

6

6

1

   

1/4

 Tilmicosin

  

1

14

7

9

7

20

24

13

5

2

2

1

 

1/4

MPC distribution

               

MPC50/MPC90

 Ceftiofura

    

1

2

4

16

19

11

17

2

17

12

2

4/64

 Cefquinomeb

     

2

1

4

14

17

24

14

10

9

8

8/64

 Florfenicolc

       

11

21

21

22

9

10

3

1

4/32

 Tilmicosind

     

2

1

7

4

10

22

10

10

5

31

16/256

  1. MIC50 and MIC90 -the drug concentration at which 50 % or 90 % of the isolates are inhibited, respectively
  2. MPC50 and MPC90-the drug concentration restricting the growth of mutant subpopulation for 50 % or 90 % respectively of the isolates tested
  3. a Testing against 103 isolates
  4. b Testing against 103 isolates
  5. c Testing against 98 isolates
  6. d Testing against 102 isolates