TY - JOUR AU - Li, Yafei AU - Zhang, Yanan AU - Ding, Huanzhong AU - Mei, Xian AU - Liu, Wei AU - Zeng, Jiaxiong AU - Zeng, Zhenling PY - 2016 DA - 2016/11/09 TI - In vitro susceptibility of four antimicrobials against Riemerella anatipestifer isolates: a comparison of minimum inhibitory concentrations and mutant prevention concentrations for ceftiofur, cefquinome, florfenicol, and tilmicosin JO - BMC Veterinary Research SP - 250 VL - 12 IS - 1 AB - Mutant prevention concentration (MPC) is an alternative pharmacodynamic parameter that has been used to measure antimicrobial activity and represents the propensities of antimicrobial agents to select resistant mutants. The concentration range between minimum inhibitory concentration (MIC) and MPC is defined as mutant selection window (MSW). The MPC and MSW parameters represent the ability of antimicrobial agents to inhibit the bacterial mutants selected. This study was conducted to determine the MIC and MPC values of four antimicrobials including ceftiofur, cefquinome, florfenicol and tilmicosin against 105 Riemerella anatipestifer isolates. SN - 1746-6148 UR - https://doi.org/10.1186/s12917-016-0796-3 DO - 10.1186/s12917-016-0796-3 ID - Li2016 ER -