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Table 2 IC50 of the extracts and chemotherapy determined by MTT assays (single treatment)

From: Effects and synergy of feed ingredients on canine neoplastic cell proliferation

  Green tea extract Pomegranate extract [40 % punicosides] Rosemary extract [70 % Carnosic Acid] Turmeric extract Black pepper extract Chemotherapya
IC50 (μg/mL) IC50 (μg/mL) IC50 (μg/mL) IC50 (μg/mL) IC50 (μg/mL) IC50
C2 11.5 48.5 11.9 4.8 21.8 12.5 nM (6.2 ng mL−1)
CMT-12 20.4 40.9 13.0 9.1 34.5 0.3 μM (163.1 ng mL−1)
D17 47.8 93.8 13.6 12.3 36.5 0.5 μM (271.8 ng mL−1)
  1. Values were determined by averaging duplicate wells in four independent experiments and using Probit analysis
  2. aC2 treated with toceranib phosphate, CMT-12 and D17 treated with doxorubicin hydrochloride