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Table 1 Challenge results in control and vaccinated sheep with live and inactivated Romanian SPPV vaccine. Antibody neutralizing titers of vaccinated sheep obtained before challenge. The infectious titer represents the maximum value obtained between day 6 and 8 post challenge

From: Comparative innocuity and efficacy of live and inactivated sheeppox vaccines

Vaccine Animals Hypersensitivity titer in TCID50 Antibody neutralizing titers in log10 Infectious titer (ID50/ml) Protection value
Per animal Group average Per animal Group average Per animal Group average Per animal Group average
Control animals 299 0 0 0 0 5.2 5,4(a) 0 0(a)
277 0 0 5.6 0
Live SPPV vaccine 977 1,6 1,6 1,9 1,7 1,5 0,75(b) 3,9 4,6(b)
928 1,6 1,26 0,5 4,9
934 1,4 1,98 0,5 4,9
999 1,8 1,5 0,5 4,9
Inactivated SPPV vaccine 948 2,7 2,2 1,98 2,2 2,1 1,4 (b) 3,3 4 (b)
941 0 2,22 2,5 2,9
949 4,5 2,46 0,5 4,9
397 1,1 1,98 0,5 4,9
398 2,5 2,46 0,5 4,9
998 0,9 1,74 0,5 4,9
973 4,5 2,46 0,5 4,9
969 1,5 2,7 4,1 1,3
  1. (a–b) indicate a significant difference in means of infectious titers and protection values between vaccinated and unvaccinated animals and between G1 and G2 at the 0.05 level
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