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Table 1 Challenge results in control and vaccinated sheep with live and inactivated Romanian SPPV vaccine. Antibody neutralizing titers of vaccinated sheep obtained before challenge. The infectious titer represents the maximum value obtained between day 6 and 8 post challenge

From: Comparative innocuity and efficacy of live and inactivated sheeppox vaccines

Vaccine

Animals

Hypersensitivity titer in TCID50

Antibody neutralizing titers in log10

Infectious titer (ID50/ml)

Protection value

Per animal

Group average

Per animal

Group average

Per animal

Group average

Per animal

Group average

Control animals

299

0

0

0

0

5.2

5,4(a)

0

0(a)

277

0

0

5.6

0

Live SPPV vaccine

977

1,6

1,6

1,9

1,7

1,5

0,75(b)

3,9

4,6(b)

928

1,6

1,26

0,5

4,9

934

1,4

1,98

0,5

4,9

999

1,8

1,5

0,5

4,9

Inactivated SPPV vaccine

948

2,7

2,2

1,98

2,2

2,1

1,4 (b)

3,3

4 (b)

941

0

2,22

2,5

2,9

949

4,5

2,46

0,5

4,9

397

1,1

1,98

0,5

4,9

398

2,5

2,46

0,5

4,9

998

0,9

1,74

0,5

4,9

973

4,5

2,46

0,5

4,9

969

1,5

2,7

4,1

1,3

  1. (a–b) indicate a significant difference in means of infectious titers and protection values between vaccinated and unvaccinated animals and between G1 and G2 at the 0.05 level