Analytical validation and establishment of reference intervals for a ‘high-sensitivity’ cardiac troponin-T assay in horses

Table 1 Comparison of ages, sexes, breeds and resting heparin plasma hscTnT concentrations in horses

Number	125	178	1	1
	Non-Competition Horses	Racing- Thoroughbreds	Clinical Case I	Clinical Case II
Median Age (Range)	5 (2–24)	9 (4–18)	11	14
Sexes	56 Mares, 69 Geldings	178 Geldings	Gelding	Mare
Breed(s)	TB, QH, Drafts, Arabians, WB	TB	TB	QH
Resting hscTnT Mean (±SD), ng/L	3.6 (±2.1)	5.4 (±3.8)	221.0^a	5723.0^b
hscTnT Median, ng/L	3.0	4.0^c	N/A	N/A
hscTnT Range, ng/L	3.0–17.0	3.0–24.0	N/A	N/A
hscTnT 95 % URL (90 % CI), ng/L	6.79 (6.0–12.0)	14.0 (10.0–18.0)	N/A	N/A
hscTnT 99 % URL (90 % CI), ng/L	16.2 (N/A)	23.2 (N/A)	N/A	N/A

Comparison of ages, sexes, breeds and resting heparin plasma hscTnT concentrations from 303 apparently healthy horses (Non-Competition Horses and Racing-Thoroughbreds) as well as two clinical cases
^aHeparin plasma hscTnT sample taken 5 h after race-induced upper respiratory crisis event
^bHeparin plasma hscTnT sample taken 41 h after initially presented to clinic
^cIndicates a significant difference from Non-Competition Horses

ISSN: 1746-6148