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Table 7 P values for selected variables in study 2 analysed by RMANCOVA

From: Effect of benazepril, robenacoxib and their combination on glomerular filtration rate in cats

Variable

Transformation

P values in RMANCOVA

P value for normality

P < 0.05 in post-hoc tests*

  

Treatment

Time

Treatment by time

Baseline

  

Plasma renin activity

Log

< 0.0001*

< 0.0001*

0.0019*

0.0048*

0.0322

C < A & D (2, 6, 12 & 24 h), D < A (24 h)

Plasma aldosterone

Log

0.0275*

0.0004 *

0.0128*

< 0.0001*

0.1342

B < A (2 h), C < A (24 h), D < A (2, 6 & 12 h), D < C (2 & 6 h)

  1. Only results of variables with a significant (P < 0.1) treatment or “treatment by time” effect are shown. For time, baseline, normality and post-hoc comparisons, P < 0.05 was defined as significant. There were no significant sex or “sex by treatment” interactions for these variables (data not shown)
  2. BWT body weight, BSA body surface area, h hour
  3. *Results were primarily interpreted from the effect with the P value shown in bold