Skip to main content

Table 5 P values for change from baseline for selected variables in study 2

From: Effect of benazepril, robenacoxib and their combination on glomerular filtration rate in cats

Variable

Sex/time

P values for comparison to baseline

Group A: Control

Group B: Benazepril

Group C: Robenacoxib

Group D: Benazepril + Robenacoxib

Iohexol clearance per BWT

M

0.0068 D

0.0003 D

< 0.0001 D

0.0002 D

 

F

0.0033 D

0.9475

0.0248 D

0.0003 D

 

Both

0.0001 D

0.0052 D

< 0.0001 D

< 0.0001 D

Iohexol clearance per BSA

M

0.0365 D

0.0006 D

< 0.0001 D

0.0002 D

 

F

0.0005 D

0.4843

0.0030 D

< 0.0001 D

 

Both

0.0002 D

0.0024 D

< 0.0001 D

< 0.0001 D

Plasma renin activity

Day 6/13 + 2 h

< 0.0001 I

< 0.0001 I

0.0012 D

< 0.0001 I

 

Day 6/13 + 6 h

0.0002 I

< 0.0001 I

0.0166 D

0.0002 I

 

Day 6/13 + 12 h

0.1776

0.0141 I

0.0010 D

0.6073

 

Day 6/13 + 24 h

0.0284 I

0.8368

< 0.0001 D

0.0522 (D)

Plasma aldosterone

Day 6/13 + 2 h

0.0211 I

0.0012 D

0.5563

0.0005 D

 

Day 6/13 + 6 h

0.3873

0.0914 (D)

0.9468

0.0022 D

 

Day 6/13 + 12 h

0.3893

0.1708

0.2046

0.0262 D

 

Day 6/13 + 24 h

0.5757

0.0020 D

0.0002 D

0.0054 D

Red blood cell count

 

< 0.0001 I

0.0093 I

0.0816 (I)

0.0758 (I)

Haematocrit

 

0.0004 I

0.0109 I

0.1306

0.0771 (I)

Haemoglobin

 

0.0001 I

0.0077 I

0.2113

0.0298 I

Prothrombin time

 

0.0008 D

0.0014 D

0.0238 D

< 0.0001 D

Activated partial thromboplastin time

 

0.0026 D

0.0077 D

0.2387

0.0515 (D)

Albumin

 

< 0.0001 I

0.0002 I

0.1479

0.0595 (I)

Alkaline phosphatase

 

0.0121 D

0.0001 D

0.0429 D

< 0.0001 D

Aspartate aminotransferase

 

0.0009 I

0.0232 I

0.1196

0.0276 I

Creatinine

 

< 0.0001 I

< 0.0001 I

< 0.0001 I

< 0.0001 I

Total protein

 

0.0004 I

0.0510 (I)

0.9288

0.7448

Urea nitrogen

 

< 0.0001 I

< 0.0001 I

< 0.0001 I

< 0.0001 I

Calcium

 

0.0004 I

0.0005 I

0.0045 I

0.2532

Chloride

 

< 0.0001 D

< 0.0001 D

< 0.0001 D

< 0.0001 D

Magnesium

 

< 0.0001 I

0.0003 I

0.0033 I

0.0022 I

Potassium

 

0.0010 D

< 0.0001 D

0.0081 D

< 0.0001 D

Sodium

 

< 0.0001 D

< 0.0001 D

0.0188 D

< 0.0001 D

Water consumption

 

0.0002 I

< 0.0001 I

< 0.0001 I

< 0.0001 I

Urine volume

 

0.0025 I

< 0.0001 I

0.0019 I

0.0003 I

Urine specific gravity

 

< 0.0001 D

< 0.0001 D

< 0.0001 D

< 0.0001 D

Fractional excretion potassium

 

0.0029 I

< 0.0001 I

0.0009 I

< 0.0001 I

  1. Only variables with at least one significant (P < 0.05) change from baseline are shown
  2. BWT body weight, BSA body surface area, F female, M male, h hour
  3. D decrease, I increase (in bold for P < 0.05). Non-bold P values and D or I in brackets for P < 0.1
Back to article page

BMC Veterinary Research

ISSN: 1746-6148

Contact us