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Table 4 Protection of vaccinated SPF chickens with inactivated oil-emulsion vaccines against challenge with the predominant variant NDVs

From: Characterization of virulent Newcastle disease viruses from vaccinated chicken flocks in Eastern China

Vaccine-Challengea

HI titer(log2)

Prior to challenge

Challenge

Protection

Strain

Route

NO. birds

Clinical signs

Mortality

La-JS22

6.3 ± 1.8

JS-01-11-Ch

ED/IN

10

0/10

0 % (0/10)

La-JS14

6.3 ± 1.8

JS-14-12-Ch

ED/IN

10

0/10

0 % (0/10)

Control-JS22

0

JS-01-11-Ch

ED/IN

5

5/5

100 % (5/5)

Control –JS14

0

JS-14-12-Ch

ED/IN

5

5/5

100 % (5/5)

La-PBS

6.3 ± 1.8

PBS

ED/IN

5

0/10

0 % (0/5)

Control-PBS

0

PBS

ED/IN

5

0/10

0 % (0/5)

  1. aLa-JS22 and Control-JS22 = Challenge with 106 EID50 JS-22-11-Ch; La-JS14 and Control-JS14 = Challenge with 106 EID50 JS-14-12-Ch