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Table 3 In vitro neutralization of C. perfringens cytotoxicity. Calves were immunized with either a C. perfringens toxin preparation (native toxins), L-lysine protected, formaldehyde inactivated C. perfringens toxins (L-lysine/formaldehyde toxoid) or a commercial multivalent formaldehyde inactivated clostridial vaccine

From: Toxin-neutralizing antibodies protect against Clostridium perfringens-induced necrosis in an intestinal loop model for bovine necrohemorrhagic enteritis

Antiserum

Inhibitory capacity (Mean ± SEM)

Native toxins

32.00 ± 0.0

L-lysine/formaldehyde toxoid

9.00 ± 7.0

Commercial formaldehyde vaccine

4.00 ± 0.0

  1. The cytotoxicity of C. perfringens supernatant to primary bovine endothelial cells was measured using a neutral red uptake (NRU) assay. The inhibitory capacity of the antiserum is expressed as the highest dilution that yields 80 % cell viability
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BMC Veterinary Research

ISSN: 1746-6148

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