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Table 1 Porcine epidemic diarrhea virus (PEDV) whole virus (WV) ELISA sensitivity (Se) and specificity (Sp) by specimen type, antibody isotype, and sample-to-positive (S/P) ratioa

From: Porcine epidemic diarrhea virus (PEDV) detection and antibody response in commercial growing pigs

Oral fluid - PEDV WV IgG ELISA

Oral fluid - PEDV WV IgA ELISA

S/P

Se (95 % CI)

Sp (95 % CI)

S/P

Se (95 % CI)

Sp (95 % CI)

 0.30

1.00 (0.92, 1.00)

0.86 (0.84, 0.89)

0.30

1.00 (0.92, 1.00)

0.88 (0.86, 0.90)

0.40

1.00 (0.92, 1.00)

0.90 (0.88, 0.92)

0.40

1.00 (0.92, 1.00)

0.96 (0.94, 0.97)

0.50

0.98 (0.87, 1.00)

0.93 (0.91, 0.94)

0.50

1.00 (0.92, 1.00)

0.98 (0.97, 0.99)

0.60

0.88 (0.74, 0.96)

0.95 (0.93, 0.96)

0.60

1.00 (0.92, 1.00)

0.99 (0.99, 1.00)

0.70

0.71 (0.55, 0.84)

0.96 (0.95, 0.97)

0.70

1.00 (0.92, 1.00)

1.00 (0.99, 1.00)

0.80

0.69 (0.53, 0.82)

0.97 (0.96, 0.98)

0.80

1.00 (0.92, 1.00)

1.00 (0.99, 1.00)

Serum - PEDV WV IgG ELISA

Serum - PEDV WV IgA ELISA

S/P

Se (95 % CI)

Sp (95 % CI)

S/P

Se (95 % CI)

Sp (95 % CI)

0.30

1.00 (0.98, 1.00)

0.95 (0.93, 0.96)

0.30

0.93 (0.88, 0.96)

1.00 (0.99, 1.00)

0.40

0.99 (0.96, 1.00)

0.98 (0.97, 0.99)

0.40

0.90 (0.86, 0.94)

1.00 (0.99, 1.00)

0.50

0.97 (0.93, 0.99)

0.99 (0.98, 1.00)

0.50

0.82 (0.76, 0.87)

1.00 (0.99, 1.00)

0.60

0.95 (0.91, 0.86)

0.99 (0.98, 1.00)

0.60

0.73 (0.67, 0.79)

1.00 (0.99, 1.00)

0.70

0.91 (0.86, 0.94)

0.99 (0.98, 1.00)

0.70

0.66 (0.59, 0.72)

1.00 (0.99, 1.00)

0.80

0.87 (0.82, 0.91)

0.99 (0.98, 1.00)

0.80

0.58 (0.51, 0.65)

1.00 (0.99, 1.00)

  1. a \( \mathrm{S}/\mathrm{P}=\frac{\left(\mathrm{sample}\ \mathrm{O}\mathrm{D}\ \hbox{--}\ \mathrm{negative}\ \mathrm{control}\ \mathrm{mean}\ \mathrm{O}\mathrm{D}\right)}{\left(\mathrm{positive}\ \mathrm{control}\ \mathrm{mean}\ \mathrm{O}\mathrm{D}\ \hbox{--}\ \mathrm{negative}\ \mathrm{control}\ \mathrm{mean}\ \mathrm{O}\mathrm{D}\right)} \)