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Table 1 Porcine epidemic diarrhea virus (PEDV) whole virus (WV) ELISA sensitivity (Se) and specificity (Sp) by specimen type, antibody isotype, and sample-to-positive (S/P) ratioa

From: Porcine epidemic diarrhea virus (PEDV) detection and antibody response in commercial growing pigs

Oral fluid - PEDV WV IgG ELISA Oral fluid - PEDV WV IgA ELISA
S/P Se (95 % CI) Sp (95 % CI) S/P Se (95 % CI) Sp (95 % CI)
 0.30 1.00 (0.92, 1.00) 0.86 (0.84, 0.89) 0.30 1.00 (0.92, 1.00) 0.88 (0.86, 0.90)
0.40 1.00 (0.92, 1.00) 0.90 (0.88, 0.92) 0.40 1.00 (0.92, 1.00) 0.96 (0.94, 0.97)
0.50 0.98 (0.87, 1.00) 0.93 (0.91, 0.94) 0.50 1.00 (0.92, 1.00) 0.98 (0.97, 0.99)
0.60 0.88 (0.74, 0.96) 0.95 (0.93, 0.96) 0.60 1.00 (0.92, 1.00) 0.99 (0.99, 1.00)
0.70 0.71 (0.55, 0.84) 0.96 (0.95, 0.97) 0.70 1.00 (0.92, 1.00) 1.00 (0.99, 1.00)
0.80 0.69 (0.53, 0.82) 0.97 (0.96, 0.98) 0.80 1.00 (0.92, 1.00) 1.00 (0.99, 1.00)
Serum - PEDV WV IgG ELISA Serum - PEDV WV IgA ELISA
S/P Se (95 % CI) Sp (95 % CI) S/P Se (95 % CI) Sp (95 % CI)
0.30 1.00 (0.98, 1.00) 0.95 (0.93, 0.96) 0.30 0.93 (0.88, 0.96) 1.00 (0.99, 1.00)
0.40 0.99 (0.96, 1.00) 0.98 (0.97, 0.99) 0.40 0.90 (0.86, 0.94) 1.00 (0.99, 1.00)
0.50 0.97 (0.93, 0.99) 0.99 (0.98, 1.00) 0.50 0.82 (0.76, 0.87) 1.00 (0.99, 1.00)
0.60 0.95 (0.91, 0.86) 0.99 (0.98, 1.00) 0.60 0.73 (0.67, 0.79) 1.00 (0.99, 1.00)
0.70 0.91 (0.86, 0.94) 0.99 (0.98, 1.00) 0.70 0.66 (0.59, 0.72) 1.00 (0.99, 1.00)
0.80 0.87 (0.82, 0.91) 0.99 (0.98, 1.00) 0.80 0.58 (0.51, 0.65) 1.00 (0.99, 1.00)
  1. a \( \mathrm{S}/\mathrm{P}=\frac{\left(\mathrm{sample}\ \mathrm{O}\mathrm{D}\ \hbox{--}\ \mathrm{negative}\ \mathrm{control}\ \mathrm{mean}\ \mathrm{O}\mathrm{D}\right)}{\left(\mathrm{positive}\ \mathrm{control}\ \mathrm{mean}\ \mathrm{O}\mathrm{D}\ \hbox{--}\ \mathrm{negative}\ \mathrm{control}\ \mathrm{mean}\ \mathrm{O}\mathrm{D}\right)} \)