From: Treatment of 5 dogs with immune-mediated thrombocytopenia using Romiplostim
Dog | Signalment | ITP – diagnoses month/year | Recurrences | Previous immunosuppressive therapy | Therapy (in addition to immunosuppressive medication) |
---|---|---|---|---|---|
1 | Bearded Collie 7-year-old, female 22 kg | 7/2012: primary ITP | 1) 10/2012 2) 3/2013 3) 9/2014 4) 10/2014 | pred 1 mg/kg twice daily + MMF 8 mg/kg twice daily Recurrence 1) Pred, cyclosporine 2) only pred 3) pred, MMF, then dexamethasone 4) pred, MMF | omeprazole, sucralfate (to prevent gastrointestinal ulcers) ursodeoxycholic acid (due to increase in liver enzymes) |
2 | Border Collie 10-year-old, female-spayed 25 kg (obese) | 2014: primary AIHA 5/2015: Evans’ syndrome (primary ITP and AIHA) | after 3 weeks | short-acting methyl-pred 10 mg/kg once, pred 0.8 mg/kg twice daily | doxycycline omeprazole, sucralfate |
3 | Poodle 3-year-old, male-neutered 25 kg | 12/2014: Evans’ syndrome (primary ITP and AIHA) | after 3 weeks | pred 1.5 mg/kg twice daily, MMF 5 mg/kg twice daily | omeprazole, sucralfate |
4 | Mixed-breed 3-year-old, female-spayed, 22 kg | ITP associated with monocytic ehrlichiosis | after 4 weeks | pred 1 mg/kg twice daily | doxycycline omeprazole, sucralfate |
5 | Mixed-breed 2.5-year-old, female 14 kg | ITP associated with monocytic ehrlichiosis | 2 weeks | pred 0.4 mg/kg once daily | chloramphenicole/imidocarb amoxicillin-clavulanic acid omeprazole, sucralfate ursodeoxycholic acid S-adenosyl-methionine |