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Table 1 Immunohistochemistry reactivity scores

From: Antiproliferative effects of masitinib and imatinib against canine oral fibrosarcoma in vitro

Protein

Dog #

% Cells

Location

Intensity

% Area

PDGFR-α

1

75

C, N

+

29.4

2

80

C, N

+

26.2

3

100

C, N

++

21.6

4

90

C, N

++

43.9

5

0

0

6

90

C, N

+

11.6

PDGFR-β

1

90

C, M

+++

34.8

2

70

C, M

++

40.8

3

100

C

+++

38.1

4

60

C

+++

23.8

5

90

C

+

19.6

6

80

C

++

21.8

Kit

1

0

0

2

0

0

3

0

0

4

0

0

5

0

0

6

0

0

VEGFR-2

1

0

0

2

0

0

3

0

0

4

0

0

5

0

0

6

0

0

  1. Subjective scoring of immunoreactivity of 6 archived canine oral fibrosarcoma cases for VEGFR-2, PDGFR-α, PDGFR-β, and Kit. The estimated percentage of tumor cells displaying immunoreactivity, the predominant location(s) of staining (C = cytoplasmic, M = membranous, or N = nuclear), and the subjective intensity of staining (+, ++, or +++) are displayed along with semi-quantitative measurement of immunoreactivity using computer image analysis software and threshold-processed photomicrographs