Fig. 2From: Effects of epidermal growth factor receptor kinase inhibition on radiation response in canine osteosarcoma cellsClonogenic survival curves. Canine OSA cells were treated with radiation only (“control”) or in combination with erlotinib at 10 μM (“erlotinib”) given 4-6 h before radiation. Experiments were repeated three times and average of results are shown. Survival fractions are plotted on a log-scale. Erlotinib treatment resulted in statistically significant reduction in cell survival of Dharma cells for radiation doses of 0, 2, 4 and 6 Gy, and statistically significant reduction in cell survival for D17 cells at 0 Gy, but did not promote enhancement of radiation effects for D17 or Abrams cell lines. *p < 0.05 indicates statistical significant reduction in clonogenic survival compared to control at the corresponding radiation doseBack to article page