The effect of miscellaneous oral dosage forms on the environmental pollution of sulfonamides in pig holdings

BMC Veterinary Research

Table 2 Amount of sulfadiazine in μg/mg sedimentation dust at 5 localizations on 4 days

Localization	Treatment		μg sulfadiazine per mg sedimentation dust
Localization	Treatment		Day 1	Day 2	Day 3	Day 4
1: Distance to the tub 2 m, height 2.10 m	Powder	2.5 mg/kg BW	< LOQ	< LOQ	< LOQ	< LOQ
		5.0 mg/kg BW	< LOQ	< LOQ	< LOQ	< LOQ
		25 mg/kg BW	0.8	1.2	1.1	1.3
	Pellets	25 mg/kg BW	< LOQ**	< LOQ**	< LOQ**	< LOQ**
	Granula	25 mg/kg BW	< LOQ**	< LOQ**	< LOQ**	< LOQ**
	Sentinels	untreated	1.3	1.9	1.0	1.1
2: Distance to the tub 0 m, height 1.40 m	Powder	2.5 mg/kg BW	< LOQ	< LOQ	< LOQ	< LOQ
		5.0 mg/kg BW	< LOQ	0.3	0.2	0.4
		25 mg/kg BW	0.6	1.3	1.8	1.7
	Pellets	25 mg/kg BW	< LOQ	< LOQ	< LOQ*	< LOQ*
	Granula	25 mg/kg BW	< LOQ	< LOQ	< LOQ*	< LOQ*
	Sentinels	untreated	1.3	1.3	1.3	1.4
3: Distance to the tub 2 m, height 1.40 m	Powder	2.5 mg/kg BW	< LOQ	< LOQ	< LOQ	< LOQ
		5.0 mg/kg BW	< LOQ	n.d.	0.1	0.1
		25 mg/kg BW	0.2	0.5	0.7	0.8
	Pellets	25 mg/kg BW	< LOQ	< LOQ	< LOQ*	< LOQ*
	Granula	25 mg/kg BW	< LOQ	< LOQ	< LOQ*	< LOQ*
	Sentinels	untreated	0.8	0.7	0.6	0.6
4: Distance to the tub 0.6 m, height 0 m	Powder	2.5 mg/kg BW	n.d.	< LOQ	< LOQ	n.d.
		5.0 mg/kg BW	0.1	0.2	0.1	0.1
		25 mg/kg BW	0.2	0.5	0.7	0.5
	Pellets	25 mg/kg BW	< LOQ	< LOQ	< LOQ*	< LOQ
	Granula	25 mg/kg BW	< LOQ	< LOQ	< LOQ*	< LOQ
	Sentinels	untreated	0.8	0.9	0.9	0.8
5: Distance to the tub 2.5 m, height 1.10 m	Powder	2.5 mg/kg BW	< LOQ	< LOQ	< LOQ	< LOQ
		5.0 mg/kg BW	< LOQ	< LOQ	< LOQ	0.1
		25 mg/kg BW	0.2	n.d.	0.9	2.8
	Pellets	25 mg/kg BW	< LOQ	< LOQ	< LOQ	< LOQ
	Granula	25 mg/kg BW	< LOQ	< LOQ	< LOQ	< LOQ
	Sentinels	untreated	0.9	1.1	1.0	1.0

BW body weight, LOQ limit of quantification; * = p < 0.05 (vs. pellets), ** = p < 0.01 (vs. pellets)

ISSN: 1746-6148