Table 2 Comparison of genotypes among the complete herd, affected and unaffected animals in herd 1. Logistic regression was used to compare affected and unaffected animals
PRNP genotype | Pre-exposurea | Scrapie positive sample | Scrapie negative sample | OR (95 % CI) | P-value |
|---|---|---|---|---|---|
IHNRQP/IHNRQP | 53 | 16 | 7 | 2.947 (1.089–7.973) | 0.033 |
IHNRQS/IHNRQP | 63 | 28 | 6 | 8.974 (3.261–24.699) | <0.005 |
IHNRQS/IHNRQS | 13 | 7 | 1 | 8.191 (0.949–70.704) | 0.055 |
MHNRQP/IHNRQS | 14 | 0 | 3 | NDǂ | – |
MHNQQS/IHNRQP | 5 | 0 | 1 | ND | – |
IHNRQP/IRNRQS | 1 | 1 | 0 | ND | – |
IHSRQP/IHNRQP | 9 | 0 | 2 | ND | – |
IHSRQP/IHNRQS | 14 | 0 | 3 | ND | – |
IHSRQP/IHSRQP | 5 | 0 | 1 | ND | – |
ihsqqs/IHNRQP | 5 | 0 | 1 | ND | – |
IHNQQS/IHNRQP | 67 | 1 | 14 | 0.057 (0.007–0.459) | 0.007 |
IHNQQS/IHNRQS | 44 | 1 | 9 | 0.098 (0.012–0.827) | 0.033 |
IHNQQS/IHNQQS | 24 | 0 | 5 | ND | – |
IHNRKS/IHNRQP | 5 | 0 | 1 | ND | – |
IHNRKS/IHNRQS | 5 | 0 | 1 | ND | – |
IHNRKS/IHNQQS | 5 | 0 | 1 | ND | – |
Total | 331 | 54 | 56 | – | – |