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Table 1 Mean ± SD ciclosporin A concentrations (ng/mL) obtained in dog blood

From: Bioequivalence study between two formulations of ciclosporin A (Cyclavance® oral solution and Atopica® soft capsules) following a single oral administration to dogs

Theoretical sampling time (h)

Atopica® soft capsules

 

Cyclavance® oral solution

 

0

BL/Q

BLQ

0.5

354.18

±206.45

491.54

±300.01

1

697.09

±224.49

712.68

±231.95

1.5

695.48

±169.80

662.00

±176.35

2

547.09

±139.04

524.47

±160.45

4

251.56

±73.61

250.15

±76.41

6

158.27

±56.38

158.55

±56.26

12

68.24

±31.77

69.86

±33.72

24

30.97

±18.92

30.65

±16.29

36

12.29

±10.40

11.96

±9.75

48

6.21

±8.24

6.73

±7.92

  1. BLQ below the lower limit of quantification