Glucose concentration in capillary blood of dairy cows obtained by a minimally invasive lancet technique and determined with three different hand-held devices

Table 3 Thresholds and corresponding test characteristics of 3 different hand-held meters to detect hyperglycemia in capillary and coccygeal blood based on Receiver Operating characteristics (ROC) analysis using a laboratory plasma glucose concentration of ≥ 60 mg/dL as reference

Device^a	Capillary blood					Coccygeal blood
	Optimized device threshold^b [mg/dL]	AUC^c [%(CI₉₅ ^d)]	Se^e [%(CI₉₅)]	Sp^f [%(CI₉₅)]	Youden-Index^g	Optimized device threshold^c [mg/dL]	AUC [%(CI₉₅)]	Se [%(CI₉₅)]	Sp [%(CI₉₅)]	Youden-Index
FSP	43	87.4 (82.5–91.3)	76.4 (66.2–84.8)	84.1 (77.3–89.5)	0.61	59	91.7 (87.5–94.9)	75.3 (65–83.8)	91.4 (85.7–95.3)	0.67
GLX	49	93.4 (89.5–96.2)	92.1 (84.5–96.8)	85.4 (78.8–90.6)	0.78	49	85.2 (80.1–89.5)	85.4 (76.3–92)	69.5 (61.5–76.8)	0.55
WGC	95	70.5 (64.3–76.3)	39.3 (29.1–50.3)	92.1 (86.5–95.8)	0.31	94	70.0 (63.8–75.7)	55.1 (44.1–65.6)	84.8 (78–90.1)	0.40

^aFSP: FreeStyle Precision, (Abbott GmbH & Co. KG, Wiesbaden, Germany), GLX: GlucoMen LX Plus (A. Menarini GmbH, Vienna, Austria), WGC: WellionVet GLUCO CALEA (MED TRUST Handelsges.m.b.H, Marz, Austria)
^bbased on Receiver Operating Characteristics (ROC) analyses
^cAUC: area under the receiver operating characteristics (ROC) curve
^dCI₉₅: 95 % confidence interval
^eSe: sensitivity
^fSp; specificity
^gYouden-Index = (Se + Sp – 1)

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