BMC Veterinary Research

Table 2 Mutagenicity of dry canine-food extracts from distilled water with S. typhimurium TA98 and TA100

From: Thai generic-brand dry canine foods: mutagenicity and the effects of feeding in vivo and in vitro

Sample	Amount mg/plate	No. of His⁺ Revertants/plate^a
Sample	Amount mg/plate	TA 98, -S9	TA 98, +S9	TA100, -S9	TA 100, +S9
DG diet	0	29.5	34	110	123
	5	42.5	49	137.5	133.5
	10	32	55.5	181.5	173
	20	39^p	68^p	258.5	190.5^e
	30	58^p	70^p	262.5^p	235^p
	40	64.5^p	87.5^p	283.5^p	190^p
AP diet	0	38	32.5	112	129
	0.5	47	55.5	100	100
	5	48.5	57	129	163
	10	31.5	58	140.5	161.5
	20	39	69	190.5	191.5
	30	42^p	70.5	191.5^p	205^e
	40	102^p	80.5^p	207^p	222^p
AL diet	0	26.5	34	110	123
	5	43	34.5	125.5	129
	10	41	57	135.5	140
	20	58^e	58.5^p	167.5	175
	30	38^p	63^p	195^p	261^p
	40	37.5^p	43^p	189^p	237.5^p
RS diet	0	26.5	42	112	129
	0.5	37	42	121	142.5
	5	62	55	150.5	183.5
	10	56	76.5	166	177.5
	20	58.5	80.5	203.5^p	212
	30	43^p	67.5^e	229.5^p	268^e
	40	61.5^p	99.5^e	261.5^p	297^p
NT diet	0	29.5	34	110	123
	5	30.5	57	117.5	171
	10	84	72	162.5	177
	20	68.5	67.5^p	222.5^p	224^p
	30	56^e	52^p	236.5^p	171.5^p
Positive control	Amount/plate
4-NQO	0.2 μg	ND	ND	1040±113	ND
	0.4 μg	195±1	ND	ND	ND
BAP	5 μg	ND	ND	ND	887±91
	10 μg	ND	523±4	ND	ND
AFB1	0.03 μg	ND	138.5±3	ND	387.5±3

^a =Mean of duplicate
^e=effect
^p=partial killing effect
ND=Not determine

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ISSN: 1746-6148

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