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Table 2 Mutagenicity of dry canine-food extracts from distilled water with S. typhimurium TA98 and TA100

From: Thai generic-brand dry canine foods: mutagenicity and the effects of feeding in vivo and in vitro

Sample Amount mg/plate No. of His+ Revertants/platea
TA 98, -S9 TA 98, +S9 TA100, -S9 TA 100, +S9
DG diet 0 29.5 34 110 123
  5 42.5 49 137.5 133.5
  10 32 55.5 181.5 173
  20 39p 68p 258.5 190.5e
  30 58p 70p 262.5p 235p
  40 64.5p 87.5p 283.5p 190p
AP diet 0 38 32.5 112 129
  0.5 47 55.5 100 100
  5 48.5 57 129 163
  10 31.5 58 140.5 161.5
  20 39 69 190.5 191.5
  30 42p 70.5 191.5p 205e
  40 102p 80.5p 207p 222p
AL diet 0 26.5 34 110 123
  5 43 34.5 125.5 129
  10 41 57 135.5 140
  20 58e 58.5p 167.5 175
  30 38p 63p 195p 261p
  40 37.5p 43p 189p 237.5p
RS diet 0 26.5 42 112 129
  0.5 37 42 121 142.5
  5 62 55 150.5 183.5
  10 56 76.5 166 177.5
  20 58.5 80.5 203.5p 212
  30 43p 67.5e 229.5p 268e
  40 61.5p 99.5e 261.5p 297p
NT diet 0 29.5 34 110 123
  5 30.5 57 117.5 171
  10 84 72 162.5 177
  20 68.5 67.5p 222.5p 224p
  30 56e 52p 236.5p 171.5p
Positive control Amount/plate     
4-NQO 0.2 μg ND ND 1040±113 ND
  0.4 μg 195±1 ND ND ND
BAP 5 μg ND ND ND 887±91
  10 μg ND 523±4 ND ND
AFB1 0.03 μg ND 138.5±3 ND 387.5±3
  1. a =Mean of duplicate
  2. e=effect
  3. p=partial killing effect
  4. ND=Not determine