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Table 1 Sample classification details

From: Inflammatory profiles in canine intervertebral disc degeneration

Samples biochemistry

Samples histopathology

# Dogs

CD dogs

NCD dogs

# Dogs

CD dogs

NCD dogs

58

40

15

10

Age – median

5 years

2 years

Age – median (range(yrs))

10 year

7 years

(range(mths – yrs))

(1–11 )

(8–12)

(2–10)

(1–10)

Spinal location

NP

AF

NP

AF

Spinal location

# IVDs

35

30

36

41

# IVDs

19

18

Cervical (C1 – T1)

13

21

10

16

Cervical (C1 – T1)

ND

ND

Thoracolumbar (T1 – L1)

21

12

2

ND

Thoracolumbar (T1 – L1)

5

8

Lumbar (L1 – S1)

11

7

23

25

Lumbar (L1 – S1)

14

10

Unknown

7

7

1

ND

Unknown

ND

ND

Degeneration

Degeneration

Grade 1 (non-surgical)

ND

ND

9a

10a

Grade 1

2

8

Grade 2

32b

32c

9

9

Grade 2

4

7

Grade 3

7

6

8

8

Grade 3

3

3

Grade 4 + 5

13d

9d

10

12 + 2

Grade 4 + 5

3 + 3

3

Displacement

Displacement

NP in situ (non-surgical)

27b,c

27b,c

9a

10a

NP in situ

ND

Nuclear extrusion

24

18

12

7

Nuclear extrusion

ND

Annular protrusion

1

2

15

24

Annular protrusion

ND

Treatment

Treatment

No treatment

9

9

14

20

No treatment

ND

Treatment

24

21

20

20

  

 NSAID < 1 wk

7

8

7

4

NSAID < 1 wk

ND

 NSAID > 1 wk

6

7

8

9

NSAID > 1 wk

ND

 Steroids < 1 wk

4

2

1

ND

Steroids < 1 wk

ND

 Steroids > 1 wk

4

3

2

2

Steroids > 1 wk

ND

 Other medication

3

1

2

5

Other medication

ND

Unknown

2

ND

2

1

Unknown

ND

  1. aSamples collected from experimental dogs
  2. b9 samples collected from experimental dogs (non-surgical); 17 samples collected in a previous study [40]
  3. c4 samples collected from experimental dogs (non-surgical); 17 samples collected in a previous study [40]
  4. d1 sample collected via fenestration
  5. eSamples collected from experimental dogs;17 samples collected in a previous study [40]