TY - JOUR AU - Dagnachew, Shimelis AU - Terefe, Getachew AU - Abebe, Getachew AU - Sirak, Asegedech AU - Bollo, Enrico AU - Barry, Dave AU - Goddeeris, Bruno PY - 2015 DA - 2015/12/23 TI - Comparative clinico-pathological observations in young Zebu (Bos indicus) cattle experimentally infected with Trypanosoma vivax isolates from tsetse infested and non-tsetse areas of Northwest Ethiopia JO - BMC Veterinary Research SP - 307 VL - 11 IS - 1 AB - The Northwest region of Ethiopia is affected by both tsetse and non-tsetse transmitted trypanosomosis with a huge impact on livestock productivity. The objective of this experimental study was to determine clinical and pathological findings in young Zebu cattle experimentally infected with Trypanosoma vivax isolates from tsetse infested and non-tsetse infested areas of Northwest Ethiopia. A total of 18 cattle (Bos indicus) aged between 6 and 12 months, purchased from a trypanosome-free and confirmed to be trypanosome negative divided into three groups of six animals were used. Animals in the first two groups (Group TT: tsetse infested isolate infected and Group NT: non-tsetse infested isolate infected) received 2 mL of infected blood from donor animals at 106 trypanosomes/mL, and the remaining group was non-infected control (NIC). Each group was observed for a period of eight consecutive weeks, daily for clinical signs and once per week for parasitaemia. Postmortem examinations were done on euthanized animals, and tissue samples were taken for histopathological analysis. SN - 1746-6148 UR - https://doi.org/10.1186/s12917-015-0625-0 DO - 10.1186/s12917-015-0625-0 ID - Dagnachew2015 ER -