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Table 3 The PK/PD parameter estimates for the fAUC/MIC index and the fAUC/MIC required for various antibacterial effects

From: Pharmacokinetics/pharmacodynamics of marbofloxacin in a Pasteurella multocida serious murine lung infection model

Parameter Unit Mean ± SD
Emax log10CFU/lung 2.08 ± 0.26
E0 log10CFU/lung −4.67 ± 0.32
fAUC/MIC for EC50 h 91.08 ± 16.49
fAUC/MIC for static effect h 40.84
fAUC/MIC for 1 log10 kill h 76.88
fAUC/MIC for 2 log10 kill h 139.34
fAUC/MIC for 3 log10 kill h 278.08