TY - JOUR AU - Qu, Ying AU - Qiu, Zhenzhen AU - Cao, Changfu AU - Lu, Yan AU - Sun, Meizhen AU - Liang, Chaoping AU - Zeng, Zhenling PY - 2015 DA - 2015/12/02 TI - Pharmacokinetics/pharmacodynamics of marbofloxacin in a Pasteurella multocida serious murine lung infection model JO - BMC Veterinary Research SP - 294 VL - 11 IS - 1 AB - Marbofloxacin is a third-generation fluoroquinolone developed solely for veterinary medicine with a broad spectrum of antibacterial activity against some Gram-positive and most Gram-negative bacteria, including the bovine respiratory tract pathogen, Pasteurella multocida. The objective of our study was to elucidate the pharmacokinetics and pharmacodynamics of marbofloxacin in a Pasteurella multocida infected murine lung model, and to estimate the magnitudes of pharmacokinetics-pharmacodynamics parameters associated with various effects. SN - 1746-6148 UR - https://doi.org/10.1186/s12917-015-0608-1 DO - 10.1186/s12917-015-0608-1 ID - Qu2015 ER -