TY - JOUR AU - Pelligand, L. AU - Suemanotham, N. AU - King, J. N. AU - Seewald, W. AU - Syme, H. AU - Smith, K. AU - Lees, P. AU - Elliott, J. PY - 2015 DA - 2015/12/03 TI - Effect of Cyclooxygenase(COX)-1 and COX-2 inhibition on furosemide-induced renal responses and isoform immunolocalization in the healthy cat kidney JO - BMC Veterinary Research SP - 296 VL - 11 IS - 1 AB - The role of cyclooxygenase(COX)-1 and COX-2 in the saluretic and renin-angiotensin responses to loop diuretics in the cat is unknown. We propose in vivo characterisation of isoform roles in a furosemide model by administering non-steroidal anti-inflammatory drugs (NSAIDs) with differing selectivity profiles: robenacoxib (COX-2 selective) and ketoprofen (COX-1 selective). SN - 1746-6148 UR - https://doi.org/10.1186/s12917-015-0598-z DO - 10.1186/s12917-015-0598-z ID - Pelligand2015 ER -