Skip to main content

Table 4 Potential candidate genes for involvement in resistance to IBV

From: The early immune response to infection of chickens with Infectious Bronchitis Virus (IBV) in susceptible and resistant birds

Gene Description Fold change GenBank Ensembl
MX1 Interferon-induced GTP-binding protein Mx. 4–24a NM_204609 ENSGALG00000016142
C1S Complement component 1, s subcomponent 2a NM_001030777 ENSGALG00000014603
IRF7 Interferon regulatory factor 7 (IRF-7). 6a NM_205372 ENSGALG00000014297
TLR3 Toll-like receptor 3 4a NM_001011691 ENSGALG00000013468
C1R Complement component 1, r subcomponent 2a XM_416518 ENSGALG00000014659
CCLi7 Chemokine ah221 8a AY037860 ENSGALG00000002343
ISG12-2 Interferon stimulated gene 12-2 16–18a NM_001001296 ENSGALG00000013575
IFITM3 Interferon induced transmembrane protein 3 4–5a KC876032 ENSGALG00000004243
CD38 ADP-ribosyl cyclase 1 4b XM_420774 ENSGALG00000014508
CD4 CD4 protein 4b NM_204649 ENSGALG00000014477
FKBP5 FK-506 binding protein 51 2b NM_001005431 ENSGALG00000000947
STAT3 Signal transducer and activator of transcription 3 (acute-phase response factor) 3b NM_001030931 ENSGALG00000003267
OASL 2'-5'-oligoadenylate synthetase-like 4c NM_205041 ENSGALG00000013723
DDT D-dopachrome tautomerase 62–72c NM_001030667 ENSGALG00000006350
SRI Sorcin 65–89c NM_001080865 ENSGALG00000008985
BLB1 MHC Class II beta 1 and 2 domains 10–22c NM_001044694 ENSGALG00000000141
IFNAR2 Interferon alpha/beta receptor 2 2–3c NM_204858 ENSGALG00000015938
TPD52L1 Tumor protein D53 homolog 12–14c NM_204215 ENSGALG00000014843
BCL2L1 BCL2-like - apoptosis regulator 1.7c NM_001025304 ENSGALG00000006211
FAIM2 Fas apoptotic inhibitory molecule 2 1.7c XM_004950568 ENSGALG00000027555
CIAPIN1 Cytokine Induced Apoptosis Inhibitor 11 1.7c NM_001005834 ENSGALG00000005706
HSCB Co-chaperone protein HscB, mitochondrial precursor (Hsc20). 8–10c XR_026662 ENSGALG00000005706
BF1 MHC class I antigen B-F minor heavy chain 13–27c NM_001097530 ENSGALG00000000178
BF2 Major class I glycoprotein precursor 7–8c NM_001031338 ENSGALG00000000178
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 16–32c NM_001006141 ENSGALG00000007652
  1. aUpregulated in response to infection in the susceptible line
  2. bHigher expression in response to infection in the resistant than in the susceptible line
  3. cInherently higher expression in the resistant line