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Table 3 Haematological and clinical biochemical results before and after weight loss

From: Assessing the adequacy of essential nutrient intake in obese dogs undergoing energy restriction for weight loss: a cohort study

Parameter Before weight loss After weight loss Reference range P value
Red blood cells ×10 12 /L 6.9 (5.3-8.1), 0, 2 6.9 (5.3-8.0), 0, 1 5.5-8.2 0.652
Haemoglobin g/L 16.0 (12.4-18.8), 0, 2 16.0 (11.3-17.9), 0, 3 12.6-19.4 0.690
Haematocrit L/L 0.48 (0.36-0.55), 0, 0 0.47 (0.35-0.54), 0, 0 0.35-0.55 0.880
Platelets ×10 9 /L 276 (13–385), 0, 2 266 (140–444), 0, 0 80-560 0.473
White blood cells ×10 9 /L 10.4 (5.1-18.7), 2, 1 8.2 (4.6-14.0), 0, 5 6.7-18.3 <0.001
Sodium mmol/L 147 (142–153), 0, 0 146 (140–151), 0, 0 140-153 0.155
Potassium mmol/L 4.6 (3.8-6.0), 1, 0 4.2 (3.7-6.0), 1, 1 3.8-5.3 0.199
Calcium mmol/L 2.8 (2.3-3.1), 3, 0 2.6 (1.8-2.9), 0, 2 2.20-2.90 <0.001
Phosphate mmol/L 1.0 (0.5-2.2), 1, 3 1.0 (0.5-1.5), 0, 5 0.8-2.0 0.058
Alanine aminotransferase U/L 44 (18–293), 13, 0 49 (18–238), 13, 0 7-50 0.893
Alkaline phosphatase U/L 74 (23–392), 11, 0 54 (26–295), 8, 0 0-100 0.065
Albumin g/L 32 (28–36), 1, 0 29 (25–36), 2, 0 25-35 <0.001
Cholesterol mmol/L 6.1 (4.1-7.9), 5, 0 5.4 (3.0-7.3), 1, 2 3.5-7.0 0.040
Creatinine μmol/L 84 (44–123), 2, 0 72 (46–114), 1, 0 20-110 0.033
Globulins g/L 31 (22–44), 2, 0 27 (23–42), 1, 0 22-40 0.012
Glucose mmol/L 5.1 (3.3-5.9), 5, 1 5.2 (3.0-7.4), 5, 1 3.5-5.5 0.210
Urea mmol/L 4.6 (1.8-7.6), 4, 5 5.2 (2.4-8.9), 1, 1 3.5-7.0 0.047
Free thyroxine pmol/L 21.0 (7.0-42.9), 2, 0 20.0 (8.4-34.0), 0, 0 6.6-40.0 0.562
  1. Data are expressed as median (range), number of results above reference range, and number below reference range
  2. P values quoted for Wilcoxon signed ranks test comparing pre- and post-weight-loss measurements. In the dogs, before and after weight loss, with low platelet counts, platelet clumps were identified on a blood smear suggesting that actual numbers were normal