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Table 3 Reported stability of drugs outside of manufacturers’ storage recommendations [11, 1523]

From: Temperatures of storage areas in large animal veterinary practice vehicles in the summer and comparison with drug manufacturers’ storage recommendations

Demonstrated to be stable Equivocal data about stability Demonstrated to be unstable
Anesthetics Anesthetics Cephalosporins
 atropine  lidocaine  cefazolin
 diazepam  naloxone  cephalothin
 midazolam Macrolides/lincosamides Other
 morphine sulfate  erythromycin  epinephrine
 phenobarbital Penicillins/aminopenicillins  heparin
Aminoglycosides  amoxicillin +/− clavulanate  oxytocin
 amikacin  ampicillin  
 gentamicin  penicillin G  
 neomycin Sulfonamides  
Fluoroquinolones  sulfamethoxazole  
 ciprofloxacin Tetracyclines  
 difloxacin  doxycycline  
 enrofloxacin  tetracycline  
 marbofloxacin Other  
 norfloxacin  dopamine  
 orfloxacin  furosemide  
Macrolides/lincosamides   
 clindamycin   
 lincomycin   
 tilmicosin   
 tulathromycin   
 tylosin   
Penicillins   
 oxacillin   
 cloxacillin   
Sulfonamides   
 sulfadimethoxine   
 sulfamethoxazole/trimethoprim   
Tetracyclines   
 chlortetracycline   
 oxytetracycline   
Other   
 calcium chloride   
 dexamethasone   
 diphenhydramine   
 sodium bicarbonate   
 thiamine   
  1. Excluded drugs include extemporaneous solutions, temperature ranges significantly different than those encountered in veterinary practice, and drugs in tissues such as urine or meat