Skip to main content
Fig. 7 | BMC Veterinary Research

Fig. 7

From: Characterization of DNA aptamers generated against the soft-shelled turtle iridovirus with antiviral effects

Fig. 7

Some selected aptamers bound STIV-infected FHM cells with a high level of specificity. a Fluorescence intensities of four selected FITC-aptamers binding to infected FHM cells. The fluorescence intensity of QA-12 was increased in STIV-infected FHM cells compared with QA-9, QA-36 and QA-92. The FITC-labeled initial library incubated with STIV-infected FHM cells were used as the control (black). b Fluorescent images of four FITC-aptamers with STIV-infected FHM cells. QA-12 bound to STIV-infected cells but not to normal cells. QA-9, QA-36, QA-92 and the library bound to neither STIV-infected cells nor normal cells. The initial library incubated with infected cells and aptamers incubated with noamal cells were used as the negative controls. c Fluorescent images of four FITC-aptamers with STIV-infected turtle tissues. QA-12 bound to STIV-infected liver and spleen tissues but not to normal tissues. QA-9, QA-36 and QA-92 bound to neither STIV-infected tissues nor normal tissues. The initial library was used as a negative control. Left: bright field; right: fluorescent. (Bars = 20 μm)

Back to article page