Table 1 Thromboelastometry and platelet function analyses in undiluted blood samples and samples diluted with 0.9 % saline, 3 % hypertonic saline, and 20 % mannitol in a ratio of 1:16 and 1:8 in 15 dogs
Variable | Baseline (undiluted) | 0.9 % NaCl (dilution 1:16) | 0.9 % NaCl (dilution 1:8) | 3 % HTS (dilution 1:16) | 3 % HTS (dilution 1:8) | 20 % mannitol (dilution 1:16) | 20 % mannitol (dilution 1:8) |
|---|---|---|---|---|---|---|---|
PFA-100 | |||||||
CtPFA (s) | 60 (51–88) | 73 (64–83) | 72 (68–81) | 77 (70–90) | 108 (84–126)*,** | 108 (89–132)* | 172 (124–300)*,**,*** |
Ex-tem | |||||||
CT (s) | 35 (28–55) | 38 (36–60) | 44 (31–62) | 37 (33–83) | 40 (34–48) | 51 (38–99)* | 90 (46–134)*,*** |
CFT (s) | 149 (131–159) | 151 (128–184) | 151 (123–175) | 186 (148–206) | 196 (176–249)*,** | 204 (158–249)* | 252 (222–314)*,**,*** |
MCF (mm) | 59 (55–62) | 56 (50–60) | 55 (53–57) | 54 (51–57) | 50 (46–53)*,** | 53 (51–56) | 49 (45–50)*,** |
Fib-tem | |||||||
CT (s) | 38 (30–43) | 41 (33–51) | 38 (32–47) | 36 (32–42) | 36 (32–43) | 54 (28–66) | 48 (38–58) |
MCF (mm) | 8 (8–10) | 7 (5–9) | 7 (6–8) | 7 (6–9) | 7 (6–9) | 7 (4–9) | 5 (4–5)*,**,*** |